Source
Adult adipose-derived stem cells are isolated from donated tissue obtained through liposuction with donor consent.
C² Aesthetic Portfolio / Professional Skincare
Biological skincare

The treatment begins in practice. The care continues at home.
FACTORFIVE uses ethically sourced adult human stem cell cultures to produce growth factor-rich conditioned media through its patent-pending Dynamic Cultured Media™ process. The cells are separated from the media before it is used in skincare.
Why FIVE? The brand focuses on five visible signs of skin aging: fine lines and wrinkles, sun spots, skin laxity, thinning skin, and uneven texture.
Explore the science FACTORFIVE on Instagram · @factorfiveskin
Distinctive Brands. Select Partnerships.
01 / The science of FACTORFIVE
FACTORFIVE oversees cell culture, media analysis, and formulation in-house, with attention to consistency from one production lot to the next.

Adult adipose-derived stem cells are isolated from donated tissue obtained through liposuction with donor consent.
The patent-pending Dynamic Cultured Media™ process supports the cells as they release growth factors and other signaling proteins into the culture media.
Multistep filtration removes the cells, leaving their secreted factors in the conditioned media. Proteomics and ELISA examine a target protein profile and help check consistency from lot to lot.
Cold formulation and liposomal encapsulation help protect delicate proteins. Select finished formulas also include copper peptides.
The distinction
“Human stem cell-derived” describes the origin of the growth factors, not living stem cells applied to the skin. FACTORFIVE emphasizes its culture process, protein testing, and the steps it takes to protect the resulting factors.
02 / Why it stands apart
A patent-pending culture process, followed by complementary protein analyses to check the conditioned media from lot to lot.
Cold processing is designed to help protect delicate proteins during formulation.
The brand uses liposomal encapsulation to help protect growth factors within its formulations.
Professional treatments, guided post-treatment care, and at-home skincare create continuity beyond a single product.
03 / The portfolio
In practice, after treatment, and at home—connected offerings that support a professional service and an ongoing routine.

Single-use, freeze-dried growth factor and exosome lyobeads are reconstituted with a hyaluronic acid hydrator for topical professional use. The two-part design is intended to protect the actives until use.
Professional use · topical application
A two-step professional peel system pairing a penetrating solution with a calming follow-up step.
In-office protocol
A guided take-home protocol with growth factor skincare for the days following an in-office treatment.
Provider-directed careRegenerative Serum, Anti-Aging Cream, Nourishing Silk, and other retail formulas extend the brand’s growth factor story into everyday care.
Retail and home regimen
A distinctive partnership
Explore how FACTORFIVE’s professional, post-treatment, and at-home offerings can fit your practice. Start a conversation with Sean →